Profhilo, Nucleofill & Analogues
Innovative preparations based on hyaluronic acid and nucleotides for skin bioremodelling. Work as moisturizers and stimulators at the cellular level.
Mechanism of Action
Profhilo uses NAHYCO technology — a unique hybrid composition of high-molecular (1,500 kDa) and low-molecular (150 kDa) hyaluronic acid. Unlike fillers, Profhilo does not cross-link HA but creates a stable fluid gel. It spreads through the tissue like a "hyaluronic cloud," stimulating four types of collagen (I, III, IV, VII) and elastin. The dual mechanism provides both deep hydration and biostimulation for comprehensive tissue remodeling without the volumizing effect of fillers.
When Is It Recommended?
Areas of Impact
Treatment Process
Consultation
Assessment of skin quality, laxity, and hydration. The doctor plans 5 injection points per side using the BAP technique.
Preparation
The skin is cleansed. No numbing is typically needed — Profhilo contains no lidocaine.
Injection
Using the BAP (Bolus And Point) technique, 0.2 ml micro-deposits are injected at 5 specific points on each side of the face.
Recovery
No downtime. Tiny bumps at injection sites resolve in 24–48 hours. Results develop progressively over 4–8 weeks.
Before & After
Bioremodeling, hydration
Key Advantages
Unique tissue remodeling without volume
Stimulates 4 types of collagen + elastin
Improves skin firmness and laxity
Only 2 sessions needed for a course
Zero downtime
Suitable for all skin types and ages
Frequently Asked Questions
How many Profhilo sessions are needed?▼
The standard protocol is 2 sessions spaced 4 weeks apart. Maintenance every 6–8 months.
How is Profhilo different from fillers?▼
Profhilo spreads like a cloud through tissues — it doesn't add volume but remodels and tightens the skin from within.
When are results visible?▼
Progressive improvement over 4–8 weeks. The skin appears more hydrated, firm, and radiant.
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Collagen Stimulators (Sculptra, Radiesse)
Preparations that stimulate your own collagen production. Create a scaffolding effect and gradual rejuvenation that builds over months.
Don't Know Which Procedure Suits You?
The doctor will select the optimal injection program during consultation
Book a Consultation